Publications

Controlling interfacial protein adsorption, desorption and aggregation in biomolecular condensates


Visser, BS., Haren, MHI. van, Lipínski, WP., Leijenhorst-Groener, KA. van, Claessens, MMAE., Queirós, MVA., Ramos, CHI., Eeftens, JM., Spruijt, E. Submitted - Preprint on Biorxiv. 2024.
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  • Biorxiv Preprint: 619145

Robust quantification of cellular mechanics using optical tweezers


Rodenburg, WS., Ebben, SFA., Eeftens, JM. Submitted - Preprint on Biorxiv. 2024.
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  • Biorxiv Preprint: 618126

Interplay of condensation and chromatin binding underlies BRD4 targeting


Strom, AR.*, Eeftens, JM.*, Polyachenko, Y., Weavver, CJ., Watanabe, HF., Bracha, D., Orlovsky, ND., Jumper, CC., Jacobs, WM., Brangwynne, CP. Molecular Biology of the Cell. 2024.
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CYSRT1: An Antimicrobial Epidermal Protein that Can Interact with Late Cornified Envelope Proteins


Niehues, H., Rikken, G., Kersten, FFJ., Eeftens, JM., Vlijmen-Willems, IMMJ. van, Rodijk-Olthuis, D., Jansen, PAM., Hendriks, WJAJ., Ederveen, THA., Schalkwijk, J., Bogaard, EH. van den., Zeeuwen, PLJM. Journal of Investigative Dermatology. 2023.
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Viscoelasticity and advective flow of RNA underlies nucleolar form and function


Riback, JA.*, Eeftens, JM.*, Lee, DSW. *, Quinodoz, SA., Donlic, A., Orlovsky, N., Wiesner, L., Beckers, L., Becker, LA., Strom, AR., Rana, U., Tolbert, M., Purse, BW., Kleiner, R., Kriwacki, R., Brangwynne, CP. Molecular Cell. 2023.
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Polycomb condensates can promote epigenetic marks but are not required for sustained chromatin compaction


Eeftens, JM., Kapoor, M., Michieletto, D., Brangwynne, CP. Nature Communications. 2022.
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Properties of repression condensates in living Ciona embryos


Treen, N., Shimobayashi, SF., Eeftens, JM., Brangwynne, CP., Levine, M. Nature Communications. 2021.
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Competing Protein-RNA Interaction Networks Control Multiphase Intracellular Organization


Sanders, DW., Kedersha, N., Lee, DSW., Strom, AR., Drake, V., Riback, JA., Bracha, D., Eeftens, JM., Iwanicki, A., Wang, A., Wei, MT., Whitney, G., Lyons, SM., Anderson, P., Jacobs, WM., Ivanov, P., Brangwynne, CP. Cell. 2020.
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Distinct Roles for Condensin’s Two ATPase Sites in Chromosome Condensation


Elbatsh, AMO., Kim, E., Eeftens, JM., Raaijmakers, JA., Weide, RH. van der, García-Nieto, A., Bravo, S., Ganji, M., Bos, J. uit de, Teunissen, H., Medema, RH., Wit, E. de, Haering, CH., Dekker, C., Rowland, BD. Molecular Cell. 2019.
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Catching DNA with hoops—biophysical approaches to clarify the mechanism of SMC proteins


Eeftens, JM., Dekker, C. Nature Structural & Molecular Biology. 2017.
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Real-time detection of condensin-driven DNA compaction reveals a multistep binding mechanism


Eeftens, JM., Bisht, S., Kerssemakers, J., Kschonsak, M., Haering, CH., Dekker, C. The EMBO Journal. 2017.
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The condensin complex is a mechanochemical motor that translocates along DNA


Terakawa, T.*, Bisht, S.*, Eeftens, JM.*, Dekker, C., Haering, CH., Greene, EC. Science. 2017.
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Condensin Smc2-Smc4 Dimers Are Flexible and Dynamic


Eeftens, JM.*, Katan, AJ.*, Kschonsak, M., Hassler, M., Wilde, L. de, Dief, E., Haering, CH., Dekker, C. Cell Reports. 2016.
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Copper-free click chemistry for attachment of biomolecules in magnetic tweezers


Eeftens, JM.*, Torre, J. van der, Burnham, DR, Dekker, C. BMC Biophysics. 2015.
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